Oral Metronomic Therapy in Hyderabad
Oral Metronomic Therapy is a new type of chemotherapy in which the patient is given anti-cancer drugs in a lower dose than the maximum tolerated dose over a long period of time repeatedly. This way of treating cancer has fewer side effects. This therapy affects both the tumor cells and tumor microenvironment in order to achieve therapeutic effects. As compared to the conventional chemotherapy, it is cost-effective as a lower dose is used for treatment. As per the results of extensive investigation of the therapy, it is very advantageous in selected groups of patients but it is undergoing clinical trials for generalized results.
The main characteristics of Oral Metronomic Therapy are as follows:
- Administration of chemotherapy frequently without interruptions.
- Instead of MTD it uses a biological optimized dose.
- It is administered orally.
- Application of hematopoietic growth factors are not needed.
- Side-effects of the treatment is relatively low.
- Potential for delayed development of resistance.
Mechanism
Metronomic therapy is multi-targeted Best cancer therapy in bandlaguda in nature that exerts direct and indirect effects on tumor cells. It is capable to inhibit tumor angiogenesis, stimulate anticancer immune response and induce tumor dormancy.
- Anti- angiogenic properties- Metronomic therapy inhibits tumor angiogenesis to exert its anti-cancer activity.
- Activation of Immunity- This therapy uses some cytotoxic drugs that possess immune-stimulatory properties.
- Induction of tumor dormancy- Through induction of apoptosis, a dynamic equilibrium state can be formed that results in tumor dormancy.
- Induction of senescence
- Four-dimensional effect
Metronomic therapy regimen is usually a combination of different drugs from various classes having immune-stimulatory, anti-angiogenic and apoptotic properties.
For more details on Oral Metronomic Therapy in Hyderabad, consult Dr. Jyosthna Elagandula, one of the leading Medical oncology specialist in bairagiguda