Oral TKIs Therapy in Hyderabad
TKIs or Tyrosine kinase inhibitors are targeted therapies that are given orally to treat many kinds of cancer. This is not a cure for cancer but it helps to manage the substances in the cancerous cells to delay or stop their growth. As a result, it can put cancer into long-term remission that helps people with certain cancers to live longer than expected. The process disrupted by TKIs has two parts:
- Growth factors- Chemicals that control the cell growth.
- Tyrosine Kinases- Enzymes inside the cells control cell division.
These two works together in which growth factor activates tyrosine kinases by flipping the switch and then it signals cells to start to divide. Cell division continues until tyrosine kinases turn it off.
Cancers treated with oral TKIs
Oral TKIs can treat many types of cancers like:
- Chronic Lymphocytic Leukemia
- Kidney cancer
- HER2-positive breast cancer
- Melanoma
- Waldenstrom macroglobulinemia
- Gastrointestinal stromal tumors
- Non-small cell lung cancer
Major benefit of Oral TKIs is that it kills cancer cells without damaging healthy cells and is a very effective alternative for other cancer treatments. There can be some minor side effects of TKIs among which fatigue, weight loss/gain or fever are very common. Maintaining an organized routine can help in reducing the impact of the treatment on daily life. Also, palliative care can be a helpful option to manage everything against this ailment as per Medical oncology doctors in attapur, Dr. Jyosthna Elagandula